Scale Up of Chemical Processes

Successful chemical process scale-up can be a formidable challenge due to a combination of several phenomena that only become manifest at a change of process scale. The aim of this online course is to provide an understanding of the fundamentals and a practical guide to predicting and avoiding common problems, thereby minimising the risk of unforeseen scale-up problems. Initially, we will identify the main challenges in scale-up and review the key chemical engineering tools required for addressing them. We will then apply these tools to approach scale-up problems which involve fluid mixing, heat transfer, mass transfer, chemical reactors and particulate processes. Finally, we will address practical issues relating to scale-up. Throughout the course we will draw on examples from a wide range of processes and unit operations. Process safety is hard-wired into the course and will be a continuous theme.